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BPC-157

Body Protection Compound-157

Animal Evidence
Pentadecapeptide (15 amino acids)PeptidesMW: 1,419.5 Da

For educational and research reference only. Not medical advice. Not for human or animal use. Research peptides are Research Use Only (RUO).

Amino Acid Sequence

Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val
Research Timeline

BPC-157 Research Milestones

An interactive map of key discoveries, clinical trials, and major findings across 8 research milestones.

1991
Discovery

Isolation from Human Gastric Juice

A protective protein (BPC) was identified in human gastric juice by a Croatian research group led by Predrag Sikirić. The larger protein showed cytoprotective effects on gastric mucosa.

1 of 8

Timeline compiled from published research literature for educational reference. Dates reflect first major publication or event; subsequent research continues to refine findings.

What is BPC-157?

BPC-157 is a lab-made peptide that is based on a small piece of a protective protein naturally found in your stomach juice. Imagine your stomach has a built-in repair kit — scientists identified one tiny piece of that kit (just 15 amino acids) and synthesized it in the lab to study how it works. It is one of the most researched peptides in animal studies for tissue healing.

Mechanism of Action

BPC-157 is hypothesized to interact with the nitric oxide (NO) system, promote angiogenesis (new blood vessel formation), and upregulate growth factor receptors. Research suggests it may modulate the FAK-paxillin pathway involved in cell migration and tissue repair. It appears to influence both the GI tract and systemic healing pathways.

Research Evidence

Human Evidence

Human Evidence

Limited human data. A few early-stage clinical trials have been registered examining BPC-157 for inflammatory bowel conditions, but comprehensive published human trial results remain limited as of current literature.

Animal Evidence

Animal Evidence

Extensive animal research spanning hundreds of studies in rats and mice. Animal models have shown observations related to tendon healing, muscle repair, bone fracture recovery, gut mucosal protection, and nerve regeneration. It is one of the most-studied peptides in preclinical tissue repair research.

Laboratory Evidence

In-Vitro / Lab

In vitro studies have examined BPC-157's effects on fibroblast proliferation, endothelial cell migration, and various growth factor pathways.

Frequently Asked Questions

What does BPC-157 stand for?

BPC stands for Body Protection Compound. The 157 refers to the specific sequence variant — it is a 15-amino-acid fragment of a larger protein found in human gastric juice.

Where does BPC-157 come from?

It is derived from a protein called BPC that is naturally present in human gastric (stomach) juice. The 157 peptide is a synthetic fragment of this naturally occurring protein.

Is BPC-157 approved for human use?

No. BPC-157 is a research peptide classified as Research Use Only (RUO). It is not approved by the FDA or any regulatory body as a drug or supplement.

Research Areas

Tissue repairGastrointestinal functionTendon and ligament researchWound healingNeuroprotection

Delivery Methods Studied

  • Injectable (subcutaneous)
  • Oral (studied in animal models)
  • Topical (experimental)

Stability Notes

BPC-157 shows notable stability in gastric juice (unlike most peptides). Lyophilized form recommended for storage. Stable at room temperature for short periods but long-term storage at -20°C is preferred.

Research Use Only

For educational and research reference only. Not medical advice. Not for human or animal use. Research peptides are Research Use Only (RUO).