Peptides that act as neurotransmitters or neuromodulators in the nervous system.
Nonapeptide
Delta Sleep-Inducing Peptide (DSIP) is a naturally occurring nonapeptide first isolated from rabbit brain tissue in 1977. It is one of the most studied sleep-related peptides and has been the subject of both animal and human research for decades.
Heptapeptide
Selank is a synthetic heptapeptide developed at the Institute of Molecular Genetics of the Russian Academy of Sciences. It is a derivative of the naturally occurring immunomodulatory peptide tuftsin with an added Pro-Gly-Pro sequence for stability.
Heptapeptide
Semax is a synthetic heptapeptide derived from ACTH (adrenocorticotropic hormone) fragments 4-7, with an added Pro-Gly-Pro stabilizing tail. Developed in Russia for cognitive and neurological research.
Nonapeptide (cyclic)
Oxytocin is a naturally occurring nonapeptide hormone produced by the hypothalamus and released by the posterior pituitary gland. It is one of the most well-known and extensively studied peptides in neuroscience.
Polypeptide (28 amino acids)
VIP is a widely distributed neuropeptide found throughout the central and peripheral nervous systems, as well as the gut. It belongs to the secretin/glucagon superfamily.
Peptides that act as neurotransmitters or neuromodulators in the nervous system.
Neuropeptides are classified based on their amino acid length, structure, origin, and biological function. This categorization helps researchers understand their potential roles and compare them to related molecules.